Compound

17beta-estradiol 4-O-(beta-D-glucuronate)

A steroid glucuronide anion that is the conjugate base of 4-hydroxy-17β-estradiol 4-O-(β-D-glucuronide) arising from deprotonation of the carboxylic acid function; major species at pH 7.3.

Definition from ChEBI (CHEBI:136937), read 2026-09-23. CC BY 4.0.

CHEBI:136937ChEBI

Open in the graph

Structure

2D depiction · 3D model shown

Loading the model…

A generated conformer of 17beta-estradiol 4-O-(beta-D-glucuronate) — one low-energy arrangement PubChem computed, not a measured structure. Hydrogens are not drawn; the formula counts them.

Class: Organic compound, anion
Formula: C24H31O9
Mass: 463.503 g/mol
Charge: -1
InChIKey: YQYZVYZSWJLJHS-WJXPAFDLSA-M
SMILES: [H][C@@]12CCc3c(ccc(O)c3O[C@@H]3O[C@H](C(=O)[O-])[C@@H](O)[C@H](O)[C@H]3O)[C@@]1([H])CC[C@]1(C)[C@@H](O)CC[C@@]21[H]
Look it up: ChEBI PubChem By InChIKey

Identity from ChEBI, geometry from PubChem. Not evidence.

What the reference databases state

Statements

1 statement

1 statement · 1 reference database · Subject: 17beta-estradiol 4-O-(beta-D-glucuronate) · Sources: Rhea

Order

4-hydroxy-17beta-estradiol is converted to 17beta-estradiol 4-O-(beta-D-glucuronate)CompoundRhea RHEA:53040Inferred only

Reactions

1 reaction

4-hydroxy-17beta-estradiol+UDP-alpha-D-glucuronate17beta-estradiol 4-O-(beta-D-glucuronate)+UDP+hydron
Catalysed by UGT1A9 or UGT2B7 or UGT1A8
Reaction pageLeft to rightBalanced
Rhea RHEA:53040CC BY 4.0Reference data

Other names

12 names

Resolves to: 17beta-estradiol 4-O-(beta-D-glucuronate)

Also called: (17beta)-3,17-dihydroxyestra-1(10),2,4-trien-4-yl beta-D-glucopyranosiduronate(17β)-3,17-dihydroxyestra-1(10),2,4-trien-4-yl β-D-glucopyranosiduronate4-hydroxy-17beta-estradiol 4-(beta-D-glucuronide)(1-)4-hydroxy-17beta-estradiol 4-beta-glucuronide(1-)4-hydroxy-17beta-estradiol 4-glucuronide(1-)4-hydroxy-17β-estradiol 4-(β-D-glucuronide)(1−)4-hydroxy-17β-estradiol 4-glucuronide(1−)4-hydroxy-17β-estradiol 4-β-glucuronide(1−)4-OHE2 4G(1-)4-OHE2 4G(1−)
Systematic name: 3,17beta-dihydroxyestra-1(10),2,4-trien-4-yl beta-D-glucopyranosiduronate3,17β-dihydroxyestra-1(10),2,4-trien-4-yl β-D-glucopyranosiduronate