Compound
16alpha,17beta-estriol 3-O-(beta-D-glucuronate)
A steroid glucuronide anion that is the conjugate base of estriol 3-O-(β-D-glucuronide) arising from deprotonation of the carboxylic acid function; major species at pH 7.3.
Definition from ChEBI (CHEBI:136649), read 2026-09-23. CC BY 4.0.
Structure
Loading the model…
- Class
- Organic compound, anion
- Formula
- C24H31O9
- Mass
- 463.503 g/mol
- Charge
- -1
- InChIKey
- UZKIAJMSMKLBQE-JRSYHJKYSA-M
- SMILES
- [H][C@@]12CCc3cc(O[C@@H]4O[C@H](C(=O)[O-])[C@@H](O)[C@H](O)[C@H]4O)ccc3[C@@]1([H])CC[C@]1(C)[C@@H](O)[C@H](O)C[C@@]21[H]
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
2 entities
2 entities reached.
0 reported hops2 assembled from the scaffold
What the reference databases state
Statements
4 statements
4 statements · 1 reference database · Subject: 16alpha,17beta-estriol 3-O-(beta-D-glucuronate) · Sources: Rhea
- 16alpha,17beta-estriol is converted to 16alpha,17beta-estriol 3-O-(beta-D-glucuronate)CompoundRhea RHEA:52468Inferred only
- 16alpha,17beta-estriol 3-O-(beta-D-glucuronate) is converted to 16alpha,17beta-estriol 3-O-(3-sulfo-beta-D-glucuronate)CompoundRhea RHEA:68668Inferred only
- 16alpha,17beta-estriol 3-O-(beta-D-glucuronate) is a substrate of CHST10ProteinRhea RHEA:68668Inferred only
- 16alpha,17beta-estriol 3-O-(beta-D-glucuronate) is transported by ABCC2ProteinRhea RHEA:86859Inferred only
Reactions
3 reactions
16alpha,17beta-estriol+UDP-alpha-D-glucuronate16alpha,17beta-estriol 3-O-(beta-D-glucuronate)+UDP+hydron
Catalysed by UGT1A10
Reaction pageLeft to rightBalanced
Rhea RHEA:52468CC BY 4.0Reference data
16alpha,17beta-estriol 3-O-(beta-D-glucuronate)+3'-phosphoadenylyl sulfate16alpha,17beta-estriol 3-O-(3-sulfo-beta-D-glucuronate)+adenosine 3',5'-bisphosphate+hydron
Catalysed by CHST10
Reaction pageLeft to rightBalanced
Rhea RHEA:68668CC BY 4.0Reference data
16alpha,17beta-estriol 3-O-(beta-D-glucuronate)+ATP(4-)+water16alpha,17beta-estriol 3-O-(beta-D-glucuronate)+ADP(3-)+hydrogenphosphate+hydron
Transported by ABCC2
Reaction pageLeft to rightBalanced
Rhea RHEA:86859CC BY 4.0Reference data
Where it reaches
1 system, 4 regions, 6 tissues, 6 transporter routes — routes, not measurements: transporters known to carry 16alpha,17beta-estriol 3-O-(beta-D-glucuronate) are expressed there, and no source reports it arriving.
Loading the model…
Other names
4 names
Resolves to: 16alpha,17beta-estriol 3-O-(beta-D-glucuronate)
- Also called
- 16alpha,17beta-estriol 3-O-(beta-D-glucuronide) (1-)16α,17β-estriol 3-O-(β-D-glucuronide) (1−)
- Systematic name
- (16alpha,17beta)-16,17-dihydroxyestra-1,3,5(10)-trien-3-yl beta-D-glucopyranosiduronate(16α,17β)-16,17-dihydroxyestra-1,3,5(10)-trien-3-yl β-D-glucopyranosiduronate