Papers/PMID:9427888
Vitamin E prophylaxis to reduce retinopathy of prematurity: a reappraisal of published trials.
The Journal of pediatrics1997The record
2 findings · 1 compound · 1 endpoint · 1 null
What it reported
How to read these marksWhat moved
1 finding
α-tocopherol — decreases retinopathy of prematurity incidence
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Finding“The overall incidence for Stage 3+ ROP was lower in the vitamin E-treated groups than in the control group (2.4% in vitamin E vs 5.3% in control).”
Quoted verbatim from Vitamin E prophylaxis to reduce retinopathy of prematurity: a reappraisal of published trials.. - Study
- meta-analysis
- Population
- Very low birth weight infants in six randomized trials of vitamin E prophylaxis; Stage 3+ (threshold) ROP
Vitamin E prophylaxis to reduce retinopathy of prematurity: a reappraisal of published trials.1997PMID:9427888Permalink
What did not
1 finding
α-tocopherol — no detected effect on retinopathy of prematurity incidence
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.FindingNull result“The overall incidence of any stage ROP was similar between the groups: 39.8% in the vitamin E group and 43.5% in the control group.”
Quoted verbatim from Vitamin E prophylaxis to reduce retinopathy of prematurity: a reappraisal of published trials.. - Study
- meta-analysis
- Population
- Very low birth weight infants in six randomized trials of vitamin E prophylaxis; any stage ROP
Vitamin E prophylaxis to reduce retinopathy of prematurity: a reappraisal of published trials.1997PMID:9427888Permalink