PapersPMID:8270187
Comparative modulating effects of captopril, diltiazem, dietary calcium and pyridoxal-5'-phosphate on gentamicin-induced nephrotoxicity in the rat.
No finding here moved its endpoint.
What did not
1 findingHow to read these marks →“Concomitant treatment with gentamicin and either Ca2+ or pyridoxal-5'-phosphate decreased serum urea level, did not significantly affect serum creatinine concentration, and significantly increased cortical GSH concentration in comparison to the values of these parameters following gentamicin treatment.”
- Study
- animal · not in humans
- Duration
- 6 days
- Population
- Rats given gentamicin 80 mg/kg/day intramuscularly for 6 days in all treated groups; pyridoxal-5'-phosphate added in one group, compared with gentamicin alone
Study record
- Design
- animal study, in vivo
- Species
- animal
- Population
- rats with gentamicin-induced nephrotoxicity
- Participants
- not reported
- Comparator
- an active treatment / no treatment
- Duration
- 6 days
- Endpoints measured
- 6