Papers/PMID:42124080
Serum Zinc Threshold and the Prognostic Impact of Zinc Supplementation in Liver Cirrhosis.
Nutrients2026The record
1 finding · 1 compound · 1 endpoint
What it reported
How to read these marksWhat moved
1 finding
Zn(2+) — decreases all-cause mortality
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.Findingreplicated ×5“In the multivariable stratified Cox proportional hazards analysis, zinc supplementation was significantly associated with a reduced risk of mortality (Hazard Ratio [HR]: 0.64; 95% CI: 0.44–0.94; p = 0.023).”
Quoted verbatim from Serum Zinc Threshold and the Prognostic Impact of Zinc Supplementation in Liver Cirrhosis.. - Study
- cohort
- Dose
- zinc acetate (98.4%) or zinc histidine (1.6%), 50-100 mg/day as formulation weight
- Population
- Adults with liver cirrhosis and baseline serum zinc below 70 µg/dL, zinc-treated vs untreated after propensity score matching (119 per group); retrospective single-centre cohort
Effect 0.64 hazard ratio, 95% CI 0.44 to 0.94
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