PapersPMID:42098865
Efficacy and safety of perioperative magnesium on postoperative pain in adult patients undergoing cardiothoracic surgeries- a systematic review and meta-analysis.
magnesium(2+)What moved
1 findingHow to read these marks →- Decreases visual analogue scale pain intensity
moderatereplicated ×4
“The overall mean difference in VAS score between the groups was − 0.85 (95% CI: -1.53 to -0.16), which was statistically significant, suggesting a lower pain score in the Mg group (Fig. 2).”
- Study
- meta-analysis
- Effect
- −0.85 mean difference, 95% CI −1.53 to −0.16
- Population
- Adults undergoing cardiothoracic surgery; five pooled randomised trials of perioperative magnesium against placebo or normal saline, pain at 24 hours after surgery on a 0-10 VAS; routes pooled (epidural, intravenous, local infiltration), magnesium given as an adjuvant to opioid with or without local anaesthetic
Study record
- Design
- meta-analysis
- Species
- human
- Population
- Adult patients undergoing cardiothoracic surgery
- Participants
- 1,140
- Comparator
- an active treatment / placebo
- Duration
- not reported
- Endpoints measured
- 8
- Declined
- a node exists but the paper states a different instrument or population