Papers/PMID:42008485
Pre-CRRT furosemide and mortality in sepsis-associated AKI: A retrospective cohort study.
PloS one2026The record
1 finding · 1 compound · 1 endpoint
What it reported
How to read these marksWhat moved
1 finding
furosemide — decreases all-cause mortality
LimitedEvidence strength: limited. Human evidence with several recorded weaknesses, or a design that tops out at limited.Finding“In the matched analysis, furosemide use was associated with significantly lower 28-day mortality (44.3% vs 58.6%; HR 0.58, 95% CI 0.46-0.73, p < 0.001).”
Quoted verbatim from Pre-CRRT furosemide and mortality in sepsis-associated AKI: A retrospective cohort study.. - Study
- cohort
- Duration
- 4 weeks
- Population
- Adults with sepsis-associated acute kidney injury requiring continuous renal replacement therapy (MIMIC-IV), propensity-matched; furosemide within 72 hours before CRRT versus none; 28-day horizon
Effect 0.58 hazard ratio, 95% CI 0.46 to 0.73
Pre-CRRT furosemide and mortality in sepsis-associated AKI: A retrospective cohort study.2026PMID:42008485Permalink