Papers/PMID:41686620
The effect of methylene blue infiltrating injection on anal pain after Milligan-Morgan surgery: A randomized controlled clinical study.
Medicine2026The record
1 finding drawn from this paper, on 1 compound across 1 endpoint.
What it reported
How to read these marksWhat moved
1 finding
methylene blue — decreases hospital length of stay
LikelyGrade B, Likely. Human evidence, limited replication or design limits.Findingreplicated ×1“Consequently, the mean length of hospital stay was significantly shorter for patients receiving MBI (3.80 ± 0.85 days) than for controls (5.43 ± 1.01 days; P <.001).”
Quoted verbatim from The effect of methylene blue infiltrating injection on anal pain after Milligan-Morgan surgery: A randomized controlled clinical study.. - Study
- RCT
- Participants
- 60
- Dose
- single intraoperative subcutaneous infiltration of 0.5-1 mL of 0.1% methylene blue per incision site, total not exceeding 5 mL
- Population
- adults with mixed haemorrhoids after Milligan-Morgan haemorrhoidectomy; secondary endpoint; reported in days; both arms received the same on-demand intravenous lornoxicam protocol
The effect of methylene blue infiltrating injection on anal pain after Milligan-Morgan surgery: A randomized controlled clinical study.2026PMID:41686620