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PapersPMID:40546137

Ablation of LAT2 Transporter Causes Intramuscular Glutamine Accumulation and Inhibition of Fasting-Induced Proteolysis.

Journal of cachexia, sarcopenia and muscle2025The record ↗

01 · finding
1
02 · compound
1
03 · endpoint
1
04 · null
0
  1. Finding, insufficient evidenceraisesSLC7A8

What moved

1 findingHow to read these marks →

  • L-glutamine — is transported by SLC7A8

    insufficientFinding

    “LAT2 has a critical role in regulating Gln efflux from skeletal muscle.”
    Quoted verbatim from Ablation of LAT2 Transporter Causes Intramuscular Glutamine Accumulation and Inhibition of Fasting-Induced Proteolysis..
    Study
    animal · not in humans
    Population
    LAT2 knockout (LAT2KO) mice, skeletal muscle, fasting

    Permalink

Study record

Read under
L-glutamine
Design
animal study, in vivo
Species
animal
Population
LAT2 knock-out (LAT2KO) mice compared with wild-type mice
Participants
not recorded
Comparator
not stated in the paper / within arm
Duration
2 days
Endpoints
1
Record
declined
Declined
this platform holds no node for the endpoint
Readings recorded
2