Papers/PMID:40427603
A Novel Ashwagandha (Withania somnifera) Formulation Mitigates Sleep Deprivation-Induced Cognitive Impairment and Oxidative Stress in a Rat Model.
Biomolecules2025The record
1 finding · 1 compound · 1 endpoint
What it reported
How to read these marksWhat moved
1 finding
Withania somnifera — decreases malondialdehyde (circulating)
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Finding“All doses of AE (SD + A1 to SD + A4) reduced serum, liver, and brain MDA levels compared to those in non-supplemented rats (p < 0.01, Figure 4).”
Quoted verbatim from A Novel Ashwagandha (Withania somnifera) Formulation Mitigates Sleep Deprivation-Induced Cognitive Impairment and Oxidative Stress in a Rat Model.. - Study
- animal · not in humans
- Duration
- 4 weeks
- Dose
- 15 or 30 mg/kg of 1.5% extract, or 5.5 or 11 mg/kg of 8% extract, once daily by oral gavage
- Population
- Male Sprague-Dawley rats (n = 7 per group) subjected to sleep deprivation for 4 weeks; comparison is against sleep-deprived rats given saline; all four AE dose groups pooled in the sentence
A Novel Ashwagandha (Withania somnifera) Formulation Mitigates Sleep Deprivation-Induced Cognitive Impairment and Oxidative Stress in a Rat Model.2025PMID:40427603An author is affiliated with a producerPermalink