Papers/PMID:40362854
Impact of a Dietary Supplementation with French Maritime Pine Bark Extract Pycnogenol® on Salivary and Serum Inflammatory Biomarkers During Non-Surgical Periodontal Therapy-A Randomized Placebo-Controlled Double-Blind Trial.
Nutrients2025The record
1 finding · 1 compound · 1 endpoint
What it reported
How to read these marksWhat moved
1 finding
Pinus pinaster — decreases interleukin-6 concentration
Evidence strength: moderate.Finding“However, after three months, significantly lower IL-6 levels were observed in the Pycnogenol® compared to the placebo group (p = 0.0409).”
Quoted verbatim from Impact of a Dietary Supplementation with French Maritime Pine Bark Extract Pycnogenol® on Salivary and Serum Inflammatory Biomarkers During Non-Surgical Periodontal Therapy-A Randomized Placebo-Controlled Double-Blind Trial.. - Study
- RCT
- Duration
- 3 months
- Dose
- 100 mg twice daily
- Population
- Adults aged 35-85 years with gingivitis, all given professional mechanical plaque removal at baseline; serum IL-6 at three months
Impact of a Dietary Supplementation with French Maritime Pine Bark Extract Pycnogenol® on Salivary and Serum Inflammatory Biomarkers During Non-Surgical Periodontal Therapy-A Randomized Placebo-Controlled Double-Blind Trial.2025PMID:4036285410.3390/nu17091546Permalink