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PapersPMID:40263915

Yerba Mate (Ilex paraguariensis St. Hill.) Tea May Have Cardiometabolic Beneficial Effects in Healthy and At-Risk Subjects: A Randomized, Controlled, Blind, Crossover Trial in Nonhabitual Consumers.

Molecular nutrition & food research2025The record ↗

findings
2
compound
1
endpoints
2
  1. Finding, limited evidencelowersTumour necrosis factor alpha concentration
  2. Finding, limited evidencelowersHOMA-IR
Study, every finding
crossover
  • “Consumption of yerba mate had a strong antiinflammatory effect, significantly decreasing plasma levels of all (but IL‐2) interleukins as well as TNF‐α and INF‐γ in all participants.”
    Population
    Healthy normocholesterolemic and hypercholesterolemic adults (non-habitual mate consumers) in a randomized crossover trial; comparator was a decaffeinated isotonic drink; both groups pooled
  • “Yerba mate reduced insulin resistance and improved insulin sensitivity in both groups according to the HOMA‐IR and QUICKI values, respectively, as shown in Table 5.”
    Population
    Healthy normocholesterolemic and hypercholesterolemic adults (non-habitual mate consumers) in a randomized crossover trial; comparator was a decaffeinated isotonic drink

Study record

Design
crossover trial
Species
human
Population
Normocholesterolemic (n = 25) and hypercholesterolemic (n = 27) nonhabitual yerba mate consumers
Participants
52
Comparator
placebo
Duration
56 days
Endpoints measured
62