PapersPMID:39987124
Does supplementation with pine bark extract improve cardiometabolic risk factors? A systematic review and meta-analysis.
- findings
- 2
- compound
- 1
- endpoints
- 2
- Study, every finding
- meta-analysis
- Dose studied, every finding
- pooled daily doses of 25 to 1322 mg
No finding here moved its endpoint.
What did not
How to read these marks →“A pooled analysis of 13 RCTs revealed no significant impact of PBE on serum TG concentrations in the PBE group (WMD: -4.19 mg/dL, 95% CI: -15.58, 7.19; P = 0.471) compared with the control group (Table 2; Fig. 5B).”
- Effect
- −4.19 mean difference, 95% CI −15.58 to 7.19
- Population
- Adults and children in randomised placebo- or no-intervention-controlled trials pooled across mixed health conditions; pooled estimate across pine bark extract products
“Pooled data analysis showed no substantial differences in serum HDL levels between the two groups (PBE vs. placebo) (WMD: 0.54 mg/dL, 95% CI: -4.60, 5.69; P = 0.837), with high heterogeneity among the RCTs (I² = 98.4%, P < 0.001).”
- Effect
- 0.54 mean difference, 95% CI −4.6 to 5.69
- Population
- Adults and children in randomised placebo-controlled trials pooled across mixed health conditions; pooled estimate across pine bark extract products
Study record
- Design
- meta-analysis
- Species
- human
- Population
- adults and children in 27 RCTs of pine bark extract supplements
- Participants
- 1,685
- Comparator
- placebo
- Duration
- not reported
- Endpoints measured
- 49