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Catalyst

Pinus pinasterFinding

Pinus pinaster has no detected effect on HDL cholesterol

no difference foundModerate evidenceFinding

01 · The sentence it was drawn from

“Pooled data analysis showed no substantial differences in serum HDL levels between the two groups (PBE vs. placebo) (WMD: 0.54 mg/dL, 95% CI: -4.60, 5.69; P = 0.837), with high heterogeneity among the RCTs (I² = 98.4%, P < 0.001).”
Quoted verbatim from Does supplementation with pine bark extract improve cardiometabolic risk factors? A systematic review and meta-analysis.
This finding among the 93 findings on its endpoint

Pinus pinaster

HDL cholesterol

no difference found

Effect as reported

0.54mean difference

CI −4.6 to 5.69

Who
Adults and children in randomised placebo-controlled trials pooled across mixed health conditions; pooled estimate across pine bark extract products
Dose studied
pooled daily doses of 25 to 1322 mg

Moderate evidencePMID 39987124 · 2025

02 · The study

Study
meta-analysis
Duration
not reported

Evidence, by strength

  • strong
  • moderatethis finding
  • limited
  • very limited
  • insufficient

03 · The paper

BMC complementary medicine and therapies
What else it reported2 findings · 0 compounds · 2 endpoints

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M705KE207ZM6TZ2A7GHP1D6W