Papers/PMID:39970876
Vitamin E (300 mg) in the treatment of MASH: A multi-center, randomized, double-blind, placebo-controlled study.
Cell reports. Medicine2025The record
1 finding · 1 compound · 1 endpoint
What it reported
How to read these marksWhat moved
1 finding
α-tocopherol — decreases interleukin-6 concentration
Evidence strength: limited.Finding“In addition, proinflammatory cytokines interleukin-6 (IL-6) decreased significantly in the vitamin E 300 mg group compared with the placebo group (−0.1 [0.7] vs. 0.3 [0.7], p = 0.04).”
Quoted verbatim from Vitamin E (300 mg) in the treatment of MASH: A multi-center, randomized, double-blind, placebo-controlled study.. - Study
- RCT
- Duration
- 22 months
- Dose
- vitamin E 300 mg daily
- Population
- Non-diabetic adults with biopsy-proven MASH, all given personalized lifestyle advice; secondary endpoint, change from baseline at 96 weeks
Vitamin E (300 mg) in the treatment of MASH: A multi-center, randomized, double-blind, placebo-controlled study.2025PMID:3997087610.1016/j.xcrm.2025.101939Permalink