Papers/PMID:39943939
The effects of Garcinia cambogia on glycaemic control and liver enzymes in adults: a systematic review and meta-analysis of randomised controlled trials.
Journal of nutritional science2025The record
3 findings · 1 compound · 3 endpoints · 3 null
What it reported
How to read these marksEvery finding here is a null result.
What did not
3 findings
Garcinia gummi-gutta — no detected effect on fasting blood glucose
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.FindingNull result“The random-effects model’s overall findings showed that taking Garcinia cambogia supplements did not significantly alter FBS levels (WMD: 1.02 mg/dl, 95% CI: −1.29, 3.33, P = 0.378) (I 2 = 52.4%, P = 0.050).”
Quoted verbatim from The effects of Garcinia cambogia on glycaemic control and liver enzymes in adults: a systematic review and meta-analysis of randomised controlled trials.. - Study
- meta-analysis
- Dose
- Garcinia cambogia extract 166 to 2800 mg/d across trials
- Population
- Adults in nine randomised trials (444 participants overall), mostly healthy; seven trials contributed to fasting blood sugar. In two trials the comparator arm received orlistat or a calorie-restricted diet, also given to the Garcinia arm; the rest used placebo.
Effect 1.02 mean difference, 95% CI -1.29 to 3.33
The effects of Garcinia cambogia on glycaemic control and liver enzymes in adults: a systematic review and meta-analysis of randomised controlled trials.2025PMID:39943939Permalink
Garcinia gummi-gutta — no detected effect on alanine aminotransferase
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.FindingNull result“The results of the pooled analysis revealed that Garcinia cambogia supplementation did not alter ALT concentrations significantly (Hedges’ g: 0.27, 95% CI: −0.20, 0.73, P = 0.264) (I 2 = 76.9%, P = 0.001).”
Quoted verbatim from The effects of Garcinia cambogia on glycaemic control and liver enzymes in adults: a systematic review and meta-analysis of randomised controlled trials.. - Study
- meta-analysis
- Dose
- Garcinia cambogia extract 166 to 2800 mg/d across trials
- Population
- Adults in nine randomised trials (444 participants overall), mostly healthy; six trials contributed to ALT. In two trials the comparator arm received orlistat or a calorie-restricted diet, also given to the Garcinia arm; the rest used placebo.
Effect 0.27 standardised mean difference, 95% CI -0.2 to 0.73
The effects of Garcinia cambogia on glycaemic control and liver enzymes in adults: a systematic review and meta-analysis of randomised controlled trials.2025PMID:39943939Permalink
Garcinia gummi-gutta — no detected effect on aspartate aminotransferase
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.FindingNull result“The pooled mean differences of six trials illustrated a non-significant effect on AST levels compared to the control group following Garcinia cambogia intervention (Hedges’ g: −0.08, 95% CI: −0.43, 0.26, P = 0.632).”
Quoted verbatim from The effects of Garcinia cambogia on glycaemic control and liver enzymes in adults: a systematic review and meta-analysis of randomised controlled trials.. - Study
- meta-analysis
- Dose
- Garcinia cambogia extract 166 to 2800 mg/d across trials
- Population
- Adults in nine randomised trials (444 participants overall), mostly healthy; six trials contributed to AST. In two trials the comparator arm received orlistat or a calorie-restricted diet, also given to the Garcinia arm; the rest used placebo.
Effect -0.08 standardised mean difference, 95% CI -0.43 to 0.26
The effects of Garcinia cambogia on glycaemic control and liver enzymes in adults: a systematic review and meta-analysis of randomised controlled trials.2025PMID:39943939Permalink