Papers/PMID:39920883
Clinical efficacy of adjunctive use of coenzyme Q10 in non-surgical periodontal treatment: A systematic review.
European journal of oral sciences2025The record
2 findings drawn from this paper, on 1 compound across 1 endpoint, 1 of them null.
What it reported
How to read these marksWhat moved
1 finding
coenzyme Q10 — increases clinical attachment level (CAL) gain
PreliminaryGrade D, Preliminary. Non-human or in vitro only.Finding“Daily oral supplementation (120 mg/day) with CoQ10 resulted in a greater mean reduction of PD by 0.41 mm (95% CI: 0.02-0.80) and a greater mean CAL gain by 0.52 mm (95% CI: 0.26-0.78) than seen in controls.”
Quoted verbatim from Clinical efficacy of adjunctive use of coenzyme Q10 in non-surgical periodontal treatment: A systematic review.. - Study
- meta-analysis
- Dose
- 120 mg/day
- Population
- adults with periodontitis receiving scaling and root planing; oral CoQ10 supplementation
Clinical efficacy of adjunctive use of coenzyme Q10 in non-surgical periodontal treatment: A systematic review.2025PMID:39920883
What did not
1 finding
coenzyme Q10 — no detected effect on clinical attachment level (CAL) gain
PreliminaryGrade D, Preliminary. Non-human or in vitro only.FindingNull result“There was no significant effect of local use of CoQ10 on reduction of PD and gain in CAL.”
Quoted verbatim from Clinical efficacy of adjunctive use of coenzyme Q10 in non-surgical periodontal treatment: A systematic review.. - Study
- meta-analysis
- Population
- adults with periodontitis receiving scaling and root planing; locally delivered (topical or intra-pocket) CoQ10
Clinical efficacy of adjunctive use of coenzyme Q10 in non-surgical periodontal treatment: A systematic review.2025PMID:39920883