Skip to content
Catalyst
Sign in

PapersPMID:39567688

Human HDAC6 senses valine abundancy to regulate DNA damage.

Nature2025The record ↗

01 · finding
1
02 · compound
1
03 · endpoint
1
04 · null
0
  1. Finding, insufficient evidenceraisesHDAC6

What moved

1 findingHow to read these marks →

  • L-valine — binds HDAC6

    insufficientFinding

    “Here we identify that human histone deacetylase 6 (HDAC6) serves as a valine sensor by directly binding valine through a primate-specific SE14 repeat domain.”
    Quoted verbatim from Human HDAC6 senses valine abundancy to regulate DNA damage..
    Study
    in vitro · not in humans
    Population
    human HDAC6 protein (exact binding-assay system not specified in the abstract)

    Permalink

Study record

Read under
L-valine
Design, as each reading recorded it
in vitro / mechanistic study
Species
cells / none
Population
human HDAC6
Participants
not recorded
Comparator
not stated in the paper
Duration
not recorded
Endpoints
1
Record
extracted
Readings recorded
2