L-valine/Finding
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Binds HDAC6
InsufficientEvidence strength: insufficient. Mechanistic inference, no evidence found, or evidence weakened below very limited.Finding“Here we identify that human histone deacetylase 6 (HDAC6) serves as a valine sensor by directly binding valine through a primate-specific SE14 repeat domain.”
Quoted verbatim from Human HDAC6 senses valine abundancy to regulate DNA damage.. - Study
- in vitro · not in humans
- Population
- human HDAC6 protein (exact binding-assay system not specified in the abstract)
Human HDAC6 senses valine abundancy to regulate DNA damage.2025PMID:39567688Permalink
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To cite this finding: https://catalystproject.ai/e/01M2T2GYSGQ4TBY53D2EQ9TJTJ