Papers/PMID:39412049
Vitamin E for people with non-alcoholic fatty liver disease.
The Cochrane database of systematic reviews2024The record
2 findings · 1 compound · 2 endpoints
What it reported
How to read these marksWhat moved
2 findings
α-tocopherol — decreases alanine aminotransferase
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.Finding“Vitamin E likely slightly reduces serum alanine transaminase (ALT) (MD -9.29, 95% CI -13.69 to -4.89; 11 trials, 708 participants; moderate certainty evidence) and aspartate aminotransferase (AST) (MD -4.90, 95% CI -7.24 to -2.57; 11 trials, 695 participants; moderate certainty evidence) levels compared with placebo or no intervention.”
Quoted verbatim from Vitamin E for people with non-alcoholic fatty liver disease.. - Study
- meta-analysis
- Participants
- 708
- Population
- People with non-alcoholic fatty liver disease (children and adults); vitamin E alone versus placebo or no intervention; 13 of 16 trials included lifestyle or low-calorie diet co-interventions
Effect -9.29 mean difference, 95% CI -13.69 to -4.89
Vitamin E for people with non-alcoholic fatty liver disease.2024PMID:39412049Permalink
α-tocopherol — decreases aspartate aminotransferase
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.Finding“Vitamin E likely slightly reduces serum alanine transaminase (ALT) (MD -9.29, 95% CI -13.69 to -4.89; 11 trials, 708 participants; moderate certainty evidence) and aspartate aminotransferase (AST) (MD -4.90, 95% CI -7.24 to -2.57; 11 trials, 695 participants; moderate certainty evidence) levels compared with placebo or no intervention.”
Quoted verbatim from Vitamin E for people with non-alcoholic fatty liver disease.. - Study
- meta-analysis
- Participants
- 695
- Population
- People with non-alcoholic fatty liver disease (children and adults); vitamin E alone versus placebo or no intervention; 13 of 16 trials included lifestyle or low-calorie diet co-interventions
Effect -4.9 mean difference, 95% CI -7.24 to -2.57
Vitamin E for people with non-alcoholic fatty liver disease.2024PMID:39412049Permalink