Papers/PMID:38644647
Effect of cholecalciferol supplementation on hand grip strength, walking speed, and expression of vitamin D receptor, interleukin-6, and insulin-like growth factor-1 in monocyte in pre-frail older adults: A randomized double-blind placebo-controlled trial.
Geriatrics & gerontology international2024The record
1 finding drawn from this paper, on 1 compound across 1 endpoint.
What it reported
How to read these marksWhat moved
1 finding
calciol — increases serum 25-hydroxyvitamin D concentration
PreliminaryGrade D, Preliminary. Non-human or in vitro only.Findingreplicated ×4“After a 12-week intervention, there was a significant increase in serum 25(OH)D levels in both groups, with the increase being higher in the cholecalciferol group than in the placebo group (49.05 vs. 24.01 ng/mL; P < 0.001).”
Quoted verbatim from Effect of cholecalciferol supplementation on hand grip strength, walking speed, and expression of vitamin D receptor, interleukin-6, and insulin-like growth factor-1 in monocyte in pre-frail older adults: A randomized double-blind placebo-controlled trial.. - Study
- RCT
- Duration
- 3 months
- Dose
- cholecalciferol 4000 IU/day for 12 weeks
- Population
- pre-frail older adults; all participants also received calcium lactate 500 mg/day