Papers/PMID:38391298
Astaxanthin Inhibits STING Carbonylation and Enhances Antiviral Responses.
Journal of immunology (Baltimore, Md. : 1950)2024The record
1 finding · 1 compound · 1 endpoint
What it reported
How to read these marksWhat moved
1 finding
astaxanthin — activates STING1
SpeculativeGrade F, Speculative. Mechanistic inference, no evidence found, or evidence weakened below D.Finding“Mechanistically, astaxanthin inhibited HSV-1 infection and oxidative stress-induced STING carbonylation and consequently promoted STING translocation to the Golgi apparatus and oligomerization, which activated STING-dependent host defenses.”
Quoted verbatim from Astaxanthin Inhibits STING Carbonylation and Enhances Antiviral Responses.. - Study
- animal · not in humans
- Population
- C57BL/6J mice and mouse primary peritoneal macrophages infected with HSV-1
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