Papers/PMID:37604307
The Effect of Zinc Supplementation on Lipid Profiles in Patients with Type 2 Diabetes Mellitus: A Systematic Review and Dose-Response Meta-Analysis of Randomized Clinical Trials.
Advances in nutrition (Bethesda, Md.)2023The record
2 findings · 1 compound · 2 endpoints
What it reported
How to read these marksWhat moved
2 findings
Zn(2+) — decreases triglycerides
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.Finding“After analyzing the results of 14 studies with 17 effect sizes, a significant reduction in serum concentrations of TG was observed following zinc supplementation (WMD: −13.08; 95% CI: −21.83, −4.34; P = 0.003).”
Quoted verbatim from The Effect of Zinc Supplementation on Lipid Profiles in Patients with Type 2 Diabetes Mellitus: A Systematic Review and Dose-Response Meta-Analysis of Randomized Clinical Trials.. - Study
- meta-analysis
- Population
- Adults with type 2 diabetes mellitus; 14 randomised trials, zinc supplement versus placebo or no zinc, some trials with a co-supplement given identically in both arms
Effect -13.08 mean difference, 95% CI -21.83 to -4.34
The Effect of Zinc Supplementation on Lipid Profiles in Patients with Type 2 Diabetes Mellitus: A Systematic Review and Dose-Response Meta-Analysis of Randomized Clinical Trials.2023PMID:37604307Permalink
Zn(2+) — decreases LDL cholesterol
LimitedEvidence strength: limited. Human evidence with several recorded weaknesses, or a design that tops out at limited.Finding“After analyzing the results of 14 studies with 17 effect sizes, a significant reduction in serum concentrations of LDL was observed following zinc supplementation (WMD: −6.18; 95% CI: −9.35, −3.02; P < 0.001).”
Quoted verbatim from The Effect of Zinc Supplementation on Lipid Profiles in Patients with Type 2 Diabetes Mellitus: A Systematic Review and Dose-Response Meta-Analysis of Randomized Clinical Trials.. - Study
- meta-analysis
- Population
- Adults with type 2 diabetes mellitus; 14 randomised trials, zinc supplement versus placebo or no zinc, some trials with a co-supplement given identically in both arms
Effect -6.18 mean difference, 95% CI -9.35 to -3.02
The Effect of Zinc Supplementation on Lipid Profiles in Patients with Type 2 Diabetes Mellitus: A Systematic Review and Dose-Response Meta-Analysis of Randomized Clinical Trials.2023PMID:37604307Permalink