PapersPMID:37522129
Effects of dietary polyphenol curcumin supplementation on metabolic, inflammatory, and oxidative stress indices in patients with metabolic syndrome: a systematic review and meta-analysis of randomized controlled trials.
- findings
- 2
- compound
- 1
- endpoints
- 2
curcumin- Study, every finding
- meta-analysis
No finding here moved its endpoint.
What did not
How to read these marks →- No detected effect on triglycerides
moderatereplicated ×5
“As such, the results of a fixed-effects model demonstrated that curcumin’s influence did not significantly lower the TG (MD = 1.28, 95% CI: -3.75 to 6.30, p = 0.62).”
- Effect
- 1.28 mean difference, 95% CI −3.75 to 6.3
- Dose studied
- pooled, 80 to 2,400 mg/day (one trial 20 mg/kg), 4 to 12 weeks
- Population
- Adults with metabolic syndrome in 8 randomised trials of curcumin supplementation versus placebo or blank, 4 to 12 weeks
- No detected effect on interleukin-6 concentration
limitedreplicated ×2
“Thus, the results of a model with random effects showed that curcumin had no discernible impact on IL-6 (MD = -1.5, 95% CI: -3.97 to 0.97, p = 0.23).”
- Effect
- −1.5 mean difference, 95% CI −3.97 to 0.97
- Dose studied
- pooled, nano-curcumin 80 mg/day and curcuminoids-piperine 1,000 mg/day
- Population
- Adults with metabolic syndrome in 2 randomised trials of curcumin supplementation versus placebo, 6 to 8 weeks
Study record
- Design
- meta-analysis
- Species
- human
- Population
- Adults with metabolic syndrome, 13 RCTs, 785 participants (373 male/412 female), predominantly from Iran
- Participants
- 785
- Comparator
- placebo
- Duration
- not reported
- Endpoints measured
- 13