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Catalyst

curcuminFinding

Curcumin has no detected effect on interleukin‑6 concentration

no difference foundLimited evidenceFindingreplicated ×2

01 · The sentence it was drawn from

“Thus, the results of a model with random effects showed that curcumin had no discernible impact on IL-6 (MD = -1.5, 95% CI: -3.97 to 0.97, p = 0.23).”
Quoted verbatim from Effects of dietary polyphenol curcumin supplementation on metabolic, inflammatory, and oxidative stress indices in patients with metabolic syndrome: a systematic review and meta-analysis of randomized controlled trials.
This finding among the 81 findings on its endpoint

curcumin

Interleukin-6 concentration

no difference found

Effect as reported

−1.5mean difference

CI −3.97 to 0.97

Who
Adults with metabolic syndrome in 2 randomised trials of curcumin supplementation versus placebo, 6 to 8 weeks
Dose studied
pooled, nano-curcumin 80 mg/day and curcuminoids-piperine 1,000 mg/day

Limited evidencePMID 37522129 · 2023

02 · The study

Study
meta-analysis
Duration
not reported

Evidence, by strength

  • strong
  • moderate
  • limitedthis finding
  • very limited
  • insufficient

03 · The paper

Frontiers in endocrinology
What else it reported2 findings · 1 compound · 2 endpoints

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M6Y5Y1AWN3XVXSDFQ3T7DHTC