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Papers/PMID:37343496

Astaxanthin inhibits oxidative stress and apoptosis in diabetic retinopathy.

Acta histochemica2023The record

1 finding · 1 compound · 1 endpoint

astaxanthin

What it reported

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What moved

1 finding

astaxanthin — inhibits KEAP1
SpeculativeGrade F, Speculative. Mechanistic inference, no evidence found, or evidence weakened below D.Finding
“Additionally, ASX could inhibit the expression of Keap1, promote the transport of Nrf2 from cytoplasm to nucleus and facilitate the expressions of HO-1, NQO1, γ-glutamylcysteine synthetase, (γ-GCS) and GPx.”
Quoted verbatim from Astaxanthin inhibits oxidative stress and apoptosis in diabetic retinopathy..
Study

animal · not in humans
Duration

6 weeks
Dose

20 mg/kg for 45 days
Population

streptozotocin-induced diabetic retinopathy rats, retinal tissue
Astaxanthin inhibits oxidative stress and apoptosis in diabetic retinopathy.2023PMID:37343496Permalink