Papers/PMID:37181363
The clinical efficacy of melatonin in the treatment of patients with COVID-19: a systematic review and meta-analysis of randomized controlled trials.
Frontiers in medicine2023The record
1 finding · 1 compound · 1 endpoint · 1 null
What it reported
How to read these marksEvery finding here is a null result.
What did not
1 finding
melatonin — no detected effect on erythrocyte sedimentation rate
LikelyGrade B, Likely. Human evidence with one recorded weakness, or capped at B by its design or by unread numbers.FindingNull result“No statistically significant effects were revealed between the groups regarding changes in ESR (MD −0.12, 95% CI −0.64 to 0.39, p = 0.64; I2 0%, p for heterogeneity = 0.67) and NLR (MD 7.31, 95% CI −15.21 to 29.84, p = 0.52; I2 87%, p for heterogeneity < 0.01) after melatonin administration.”
Quoted verbatim from The clinical efficacy of melatonin in the treatment of patients with COVID-19: a systematic review and meta-analysis of randomized controlled trials.. - Study
- meta-analysis
- Population
- hospitalized adults with COVID-19 receiving melatonin plus standard care versus control (predominantly standard care alone, two trials placebo-controlled)
Effect -0.12 mean difference, 95% CI -0.64 to 0.39
The clinical efficacy of melatonin in the treatment of patients with COVID-19: a systematic review and meta-analysis of randomized controlled trials.2023PMID:37181363Permalink