Papers/PMID:36903391
Berberine-Based Carbon Quantum Dots Improve Intestinal Barrier Injury and Alleviate Oxidative Stress in C57BL/6 Mice with 5-Fluorouracil-Induced Intestinal Mucositis by Enhancing Gut-Derived Short-Chain Fatty Acids Contents.
Molecules (Basel, Switzerland)2023The record
1 finding · 1 compound · 1 endpoint
What it reported
How to read these marksWhat moved
1 finding
berberine — inhibits NLRP3
PreliminaryGrade D, Preliminary. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Findingreplicated ×1“Compared with the findings in 5-FU group, the expression level of NLRP3 in the spleen significantly decreased and that of IL-10 significantly increased in the Ber-CD and Con-Ber groups (p < 0.05).”
Quoted verbatim from Berberine-Based Carbon Quantum Dots Improve Intestinal Barrier Injury and Alleviate Oxidative Stress in C57BL/6 Mice with 5-Fluorouracil-Induced Intestinal Mucositis by Enhancing Gut-Derived Short-Chain Fatty Acids Contents.. - Study
- animal · not in humans
- Duration
- 3 days
- Dose
- native berberine (Con-Ber) 5 mg/kg/day, intraperitoneal, days 3-5
- Population
- C57BL/6 mice with 5-fluorouracil-induced intestinal mucositis, spleen
Berberine-Based Carbon Quantum Dots Improve Intestinal Barrier Injury and Alleviate Oxidative Stress in C57BL/6 Mice with 5-Fluorouracil-Induced Intestinal Mucositis by Enhancing Gut-Derived Short-Chain Fatty Acids Contents.2023PMID:36903391Permalink