berberine/Finding
One finding, on its own
A single claim from the graph, with the grade computed from its study, the sentence it was drawn from, and the paper. This address does not change.
Inhibits NLRP3
PreliminaryGrade D, Preliminary. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Findingreplicated ×1“Compared with the findings in 5-FU group, the expression level of NLRP3 in the spleen significantly decreased and that of IL-10 significantly increased in the Ber-CD and Con-Ber groups (p < 0.05).”
Quoted verbatim from Berberine-Based Carbon Quantum Dots Improve Intestinal Barrier Injury and Alleviate Oxidative Stress in C57BL/6 Mice with 5-Fluorouracil-Induced Intestinal Mucositis by Enhancing Gut-Derived Short-Chain Fatty Acids Contents.. - Study
- animal · not in humans
- Duration
- 3 days
- Dose
- native berberine (Con-Ber) 5 mg/kg/day, intraperitoneal, days 3-5
- Population
- C57BL/6 mice with 5-fluorouracil-induced intestinal mucositis, spleen
Berberine-Based Carbon Quantum Dots Improve Intestinal Barrier Injury and Alleviate Oxidative Stress in C57BL/6 Mice with 5-Fluorouracil-Induced Intestinal Mucositis by Enhancing Gut-Derived Short-Chain Fatty Acids Contents.2023PMID:36903391Permalink
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To cite this finding: https://catalystproject.ai/e/01M3P2TTYGH2MNRE3168YNFV9V