Papers/PMID:36749131
The Effect of Magnesium Supplementation on Vascular Calcification in CKD: A Randomized Clinical Trial (MAGiCAL-CKD).
Journal of the American Society of Nephrology : JASN2023The record
1 finding · 1 compound · 1 endpoint
What it reported
How to read these marksWhat moved
1 finding
magnesium(2+) — increases serum magnesium concentration
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Findingreplicated ×3“Despite significant increases in plasma magnesium among study participants who received magnesium compared with those who received placebo, magnesium supplementation did not slow the progression of vascular calcification in study participants.”
Quoted verbatim from The Effect of Magnesium Supplementation on Vascular Calcification in CKD: A Randomized Clinical Trial (MAGiCAL-CKD).. - Study
- RCT
- Duration
- 12 months
- Dose
- oral magnesium hydroxide 15 mmol twice daily
- Population
- Adults with predialysis chronic kidney disease (eGFR 15 to 45 ml/min)
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