Papers/PMID:36432623
Potential Benefits of Selenium Supplementation in Reducing Insulin Resistance in Patients with Cardiometabolic Diseases: A Systematic Review and Meta-Analysis.
Nutrients2022The record
2 findings · 1 compound · 2 endpoints
What it reported
How to read these marksWhat moved
2 findings
selenium atom — increases HDL cholesterol
Evidence strength: moderate.Finding“The pooled results from the random-effects model indicated that selenium supplementation remarkably increased HDL-C levels (SMD: 0.97, 95% CI [0.26, 1.68], p = 0.007), with high heterogeneity across studies (I2 = 92%) (Supplementary Figure S5).”
Quoted verbatim from Potential Benefits of Selenium Supplementation in Reducing Insulin Resistance in Patients with Cardiometabolic Diseases: A Systematic Review and Meta-Analysis.. - Study
- meta-analysis
- Population
- Patients with cardiometabolic diseases, nine randomised placebo-controlled trials, all in Iran
Effect 0.97 standardised mean difference, 95% CI 0.26 to 1.68
Potential Benefits of Selenium Supplementation in Reducing Insulin Resistance in Patients with Cardiometabolic Diseases: A Systematic Review and Meta-Analysis.2022PMID:3643262310.3390/nu14224933Permalink
selenium atom — decreases HOMA-IR
Evidence strength: moderate.Finding“Pooled results obtained by employing a random-effects model demonstrated that selenium supplementation remarkably lowered serum insulin levels (SMD: −0.53, 95% CI [−0.84, −0.21], p = 0.001) and decreased HOMA-IR (SMD: −0.50, 95% CI [−0.86, −0.14], p = 0.006) (and Figure 5).”
Quoted verbatim from Potential Benefits of Selenium Supplementation in Reducing Insulin Resistance in Patients with Cardiometabolic Diseases: A Systematic Review and Meta-Analysis.. - Study
- meta-analysis
- Population
- Patients with cardiometabolic diseases (diabetes, cardiovascular disease, obesity), 10 randomised double-blind placebo-controlled trials, all in Iran; treatment 4 to 24 weeks
Effect -0.5 standardised mean difference, 95% CI -0.86 to -0.14
Potential Benefits of Selenium Supplementation in Reducing Insulin Resistance in Patients with Cardiometabolic Diseases: A Systematic Review and Meta-Analysis.2022PMID:3643262310.3390/nu14224933Permalink