Papers/PMID:35684079
Consumption of Low Dose Fucoxanthin Does Not Prevent Hepatic and Adipose Inflammation and Fibrosis in Mouse Models of Diet-Induced Obesity.
Nutrients2022The record
1 finding · 1 compound · 1 endpoint · 1 null
What it reported
How to read these marksEvery finding here is a null result.
What did not
1 finding
fucoxanthin — no detected effect on alanine aminotransferase
SpeculativeGrade F, Speculative. Mechanistic inference, no evidence found, or evidence weakened below D.FindingNull result“No significant differences were present in liver triglyceride and total cholesterol, hepatic fat accumulation, and serum alanine aminotransferase levels between control and FCX-fed mice regardless of whether they were on an HFC or HFS diet.”
Quoted verbatim from Consumption of Low Dose Fucoxanthin Does Not Prevent Hepatic and Adipose Inflammation and Fibrosis in Mouse Models of Diet-Induced Obesity.. - Study
- animal · not in humans
- Dose
- 0.015% or 0.03% w/w FCX in HFC diet, 12 weeks; 0.01% w/w FCX in HFS diet, 8 weeks
- Population
- C57BL/6J mice, pooled across HFC (high-fat/high-sucrose/high-cholesterol) and HFS (high-fat/high-sucrose) diet-induced obesity models, FCX-supplemented diet vs same diet without FCX
Consumption of Low Dose Fucoxanthin Does Not Prevent Hepatic and Adipose Inflammation and Fibrosis in Mouse Models of Diet-Induced Obesity.2022PMID:35684079Permalink