PapersPMID:34986852
Association between dietary choline and betaine intake and 10.6-year cardiovascular disease in adults.
No finding here moved its endpoint.
What did not
1 findingHow to read these marks →“Results of Cox proportional hazard regression indicated no association between dietary energy-adjusted total choline (HR: 0.80; 95% CI: 0.56–1.23) nor energy-adjusted betaine (HR: 0.96; 95% CI: 0.64–1.44) and the incidence of CVD (Table 3).”
- Study
- cohort
- Effect
- 0.8 hazard ratio, 95% CI 0.56 to 1.23
- Dose studied
- energy-adjusted dietary total choline (sum of free choline, glycerophosphocholine, phosphocholine, phosphatidylcholine and sphingomyelin), tertiles
- Population
- 2606 adults without prior cardiovascular disease in the Tehran Lipid and Glucose Study, median follow-up 10.6 years, 187 incident events; dietary intake by 168-item food-frequency questionnaire
Study record
- Design
- cohort study
- Species
- human
- Population
- Adults without prior CVD in the Tehran Lipid and Glucose Study, third wave (2006-2008)
- Participants
- 2,606
- Comparator
- observational
- Duration
- 3,872 days
- Endpoints measured
- 32
choline