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Catalyst

PapersPMID:34817582

Association of L-α Glycerylphosphorylcholine With Subsequent Stroke Risk After 10 Years.

JAMA network open2021The record ↗

  1. Finding, limited evidenceraisesIncidence of stroke

What moved

1 findingHow to read these marks →
  • Increases incidence of stroke

    limited

    “Compared with α-GPC nonusers, individuals who were prescribed α-GPC had a higher risk for total stroke (aHR, 1.46; 95% CI, 1.43-1.48), ischemic stroke (aHR, 1.36; 95% CI, 1.33-1.39), and hemorrhagic stroke (aHR, 1.36; 95% CI, 1.28-1.44).”
    Study
    cohort
    Effect
    1.36 hazard ratio, 95% CI 1.28 to 1.44
    Population
    Korean National Health Insurance adults aged 50 years or older without prior stroke, TIA or antidementia drug use; alpha-GPC prescribed for at least 1 day in 2006 to 2008 versus nonusers; hemorrhagic stroke subtype, total cohort

Study record

Design
cohort study
Species
human
Population
Men and women aged 50 years or older in South Korea without prior stroke, TIA or antidementia drug use (National Health Insurance Service)
Participants
12,008,977
Comparator
no treatment / observational
Duration
not reported
Endpoints measured
93