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Catalyst

sn-glycerol 3-phosphocholineFinding

Sn-glycerol 3-phosphocholine increases incidence of stroke

raisesLimited evidenceFinding

01 · The sentence it was drawn from

“Compared with α-GPC nonusers, individuals who were prescribed α-GPC had a higher risk for total stroke (aHR, 1.46; 95% CI, 1.43-1.48), ischemic stroke (aHR, 1.36; 95% CI, 1.33-1.39), and hemorrhagic stroke (aHR, 1.36; 95% CI, 1.28-1.44).”
Quoted verbatim from Association of L-α Glycerylphosphorylcholine With Subsequent Stroke Risk After 10 Years.
This finding among the 18 findings on its endpoint

sn-glycerol 3-phosphocholine

Incidence of stroke

raises

Effect as reported

1.36hazard ratio

CI 1.28 to 1.44

Who
Korean National Health Insurance adults aged 50 years or older without prior stroke, TIA or antidementia drug use; alpha-GPC prescribed for at least 1 day in 2006 to 2008 versus nonusers; hemorrhagic stroke subtype, total cohort
Dose studied
not reported

Limited evidencePMID 34817582 · 2021

02 · The study

Study
cohort
Duration
not reported

Evidence, by strength

  • strong
  • moderate
  • limitedthis finding
  • very limited
  • insufficient

03 · The paper

JAMA network open
What else it reported1 finding · 1 compound · 1 endpoint

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M6ZFAK8M2E4V1EMK7Y2X73GR