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PapersPMID:34711479

Treatment with L-Citrulline in patients with post-polio syndrome: A single center, randomized, double blind, placebo-controlled trial.

Neuromuscular disorders2021The record ↗

  1. Finding, very limited evidenceno difference foundSix-minute walk test distance

No finding here moved its endpoint.

What did not

1 findingHow to read these marks →
  • No detected effect on six-minute walk test distance

    very limited

    “Patients receiving L-Citrulline walked 17.5 longer in the 6 min walking distance test when compared to placebo group, however not statistically significant (95% CI = -14.69; 49.68, p = 0.298).”
    Study
    RCT
    Duration
    6 months
    Dose studied
    15 g L-citrulline daily for 24 weeks
    Population
    Patients with post-polio syndrome

Study record

Design
randomised controlled trial
Species
human
Population
Patients with post-polio syndrome (PPS); L-citrulline, form not stated in the abstract
Participants
29
Comparator
placebo
Duration
168 days
Endpoints measured
4