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Catalyst

L-citrullineFinding

L-citrulline has no detected effect on six-minute walk test distance

no difference foundVery limited evidenceFinding

01 · The sentence it was drawn from

“Patients receiving L-Citrulline walked 17.5 longer in the 6 min walking distance test when compared to placebo group, however not statistically significant (95% CI = -14.69; 49.68, p = 0.298).”
Quoted verbatim from Treatment with L-Citrulline in patients with post-polio syndrome: A single center, randomized, double blind, placebo-controlled trial.
This finding among the 3 findings on its endpoint

L-citrulline

Six-minute walk test distance

no difference found

Who
Patients with post-polio syndrome
Dose studied
15 g L-citrulline daily for 24 weeks

Very limited evidencePMID 34711479 · 2021

02 · The study

Study
RCT
Duration
6 months

Evidence, by strength

  • strong
  • moderate
  • limited
  • very limitedthis finding
  • insufficient

03 · The paper

Neuromuscular disorders
What else it reported1 finding · 1 compound · 1 endpoint

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M6ZFAX9KHRBB3Z373P67EQG5