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PapersPMID:34684621

The Effect of Daily Methylsulfonylmethane (MSM) Consumption on High-Density Lipoprotein Cholesterol in Healthy Overweight and Obese Adults: A Randomized Controlled Trial.

Nutrients2021The record ↗

findings
2
compound
1
endpoints
2
no difference found
1
  1. Finding, limited evidencelowersC-reactive protein concentration
  2. Finding, limited evidenceno difference foundTotal antioxidant capacity
Study, every finding
RCT · 4 months
Dose studied, every finding
3 g/day MSM (OptiMSM) vs placebo capsules of white rice flour

What moved

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  • Decreases C-reactive protein concentration

    limited

    “CRP was significantly lower in MSM compared to placebo at week 16 (p = 0.04).”
    Interests
    Industry funded
    Population
    Healthy overweight or obese adults (BMI 25 or above), 22 completers; week 16 timepoint

What did not

  • No detected effect on total antioxidant capacity

    limited

    “The total antioxidant capacity of the serum was not different between the MSM and placebo group (Table 3).”
    Interests
    Industry funded
    Population
    Healthy overweight or obese adults (BMI 25 or above), 22 completers

Study record

Design
randomised controlled trial
Species
human
Population
healthy overweight and obese adults, BMI 25 kg/m2 or above
Participants
22
Comparator
placebo
Duration
112 days
Endpoints measured
26