Papers/PMID:33673704
Fucoxanthin Suppresses Osteoclastogenesis via Modulation of MAP Kinase and Nrf2 Signaling.
Marine drugs2021The record
1 finding · 1 compound · 1 endpoint
What it reported
How to read these marksWhat moved
1 finding
fucoxanthin — inhibits EPHB2
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Finding“The treatment of RAW264.7 cells with FX significantly reduced the phosphorylation of ERK and p38 in a concentration-dependent manner.”
Quoted verbatim from Fucoxanthin Suppresses Osteoclastogenesis via Modulation of MAP Kinase and Nrf2 Signaling.. - Study
- in vitro · not in humans
- Duration
- 4 days
- Dose
- 0, 1, 2.5 and 5 uM FX
- Population
- RAW264.7 murine macrophage cells stimulated with sRANKL or TNF-alpha/IL-6
Fucoxanthin Suppresses Osteoclastogenesis via Modulation of MAP Kinase and Nrf2 Signaling.2021PMID:33673704Permalink