Papers/PMID:33275775
Effects of selenium supplementation on pregnancy outcomes and disease progression in HIV-infected pregnant women in Lagos: A randomized controlled trial.
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics2021The record
2 findings · 1 compound · 2 endpoints · 1 null
What it reported
How to read these marksWhat moved
1 finding
selenium atom — decreases preterm birth incidence
Evidence strength: moderate.Finding“On performing the multivariate analysis of all variables at end-line, mothers on prenatal selenium supplements have a statistically significant lower risk of preterm delivery compared with women in the placebo arm (RR 0.32, 95% CI 0.11–0.95; P = 0.039).”
Quoted verbatim from Effects of selenium supplementation on pregnancy outcomes and disease progression in HIV-infected pregnant women in Lagos: A randomized controlled trial.. - Study
- RCT
- Dose
- 200 μg elemental selenium tablet daily from enrolment until delivery
- Population
- HIV-seropositive pregnant women in Lagos, 14–27 weeks gestation at enrolment; all received standard prenatal iron, folic acid and malaria chemoprophylaxis; multivariate-adjusted estimate
Effect 0.32 risk ratio, 95% CI 0.11 to 0.95
Effects of selenium supplementation on pregnancy outcomes and disease progression in HIV-infected pregnant women in Lagos: A randomized controlled trial.2021PMID:3327577510.1002/ijgo.13514Permalink
What did not
1 finding
selenium atom — no detected effect on adverse event occurrence (oral or enteral supplement)
Evidence strength: moderate.FindingNull result“However, the use of selenium supplements had no statistically significant effects on the risks of perinatal death (P = 0.932) and adverse drug events (P = 0.898) (Table 2).”
Quoted verbatim from Effects of selenium supplementation on pregnancy outcomes and disease progression in HIV-infected pregnant women in Lagos: A randomized controlled trial.. - Study
- RCT
- Dose
- 200 μg elemental selenium tablet daily from enrolment until delivery
- Population
- HIV-seropositive pregnant women in Lagos, 14–27 weeks gestation at enrolment; 34 women overall recorded adverse drug events
Effects of selenium supplementation on pregnancy outcomes and disease progression in HIV-infected pregnant women in Lagos: A randomized controlled trial.2021PMID:3327577510.1002/ijgo.13514Permalink