No finding here moved its endpoint.
What did not
1 findingHow to read these marks →- No detected effect on all-cause mortality
very limited
“A pooled analysis of eight trials indicates there may be little or no difference in all-cause mortality comparing citicoline with placebo (17.3% versus 18.5%; RR 0.94, 95% CI 0.83 to 1.07; I² = 0%; low-quality evidence due to risk of bias).”
- Study
- meta-analysis
- Effect
- 0.94 risk ratio, 95% CI 0.83 to 1.07
- Dose studied
- citicoline 500 mg to 2000 mg per day, oral, intravenous or both
- Population
- Adults with acute ischaemic stroke; pooled analysis of eight of ten randomised trials, citicoline given orally, intravenously or both
Study record
- Design
- meta-analysis
- Species
- human
- Population
- people with acute ischemic stroke
- Participants
- 4,281
- Comparator
- placebo
- Duration
- not reported
- Endpoints measured
- 5