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PapersPMID:32799362

A randomized, triple-blind, placebo-controlled, parallel study to evaluate the efficacy of a freshwater marine collagen on skin wrinkles and elasticity.

Journal of cosmetic dermatology2021The record ↗

findings
2
compound
1
endpoints
2
no difference found
1
  1. Finding, moderate evidencelowersFacial wrinkle severity
  2. Finding, moderate evidenceno difference foundSkin elasticity (suction-probe viscoelasticity)
Study, every finding
RCT · 3 months
Dose studied, every finding
10 g/day hydrolyzed freshwater fish collagen powder (Vinh Wellness Collagen, Pangasius hypophthalmus) in at least 100 mL water each morning on an empty stomach; placebo maltodextrin
  • “After 12 weeks, there was a 24% reduction in wrinkle score on the right side of the face for participants supplemented with VWC compared to placebo (P =.035).”
    Interests
    Industry funded
    Population
    Women aged 45 to 60 years with visible signs of natural ageing and photoaging of the face; nasolabial wrinkles, right side of the face only, 12 weeks

What did not

  • “There was no significant difference in cheek skin elasticity between VWC and placebo groups after 12 weeks.”
    Interests
    Industry funded
    Population
    Women aged 45 to 60 years with visible signs of natural ageing and photoaging of the face; whole per-protocol population, cheek, 12 weeks

Study record

Design
randomised controlled trial
Species
human
Population
Women aged 45 to 60 years with visible signs of natural and photoaging on the face
Participants
50
Comparator
placebo
Duration
84 days
Endpoints measured
80