Papers/PMID:32451277
Effects of zinc supplementation on lipid profile in patients with type 2 diabetes mellitus: A systematic review and meta-analysis of randomized controlled trials.
Nutrition, metabolism, and cardiovascular diseases : NMCD2020The record
2 findings · 1 compound · 2 endpoints
What it reported
How to read these marksWhat moved
2 findings
Zn(2+) — decreases triglycerides
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Findingreplicated ×3“Combining 9 effect sizes from 9 RCTs, we found a significant lowering effect of zinc supplementation on serum levels of TG (weighted mean difference (WMD): -17.08, 95% CI: -30.59, -3.58 mg/dL, P = 0.01) and TC (WMD: -26.16, 95% CI: -49.69, -2.62 mg/dL, P = 0.02).”
Quoted verbatim from Effects of zinc supplementation on lipid profile in patients with type 2 diabetes mellitus: A systematic review and meta-analysis of randomized controlled trials.. - Study
- meta-analysis
- Population
- Patients with type 2 diabetes mellitus; 9 randomized controlled trials, 424 patients overall
Effect -17.08 mean difference, 95% CI -30.59 to -3.58
Effects of zinc supplementation on lipid profile in patients with type 2 diabetes mellitus: A systematic review and meta-analysis of randomized controlled trials.2020PMID:32451277Permalink
Zn(2+) — decreases total cholesterol (TC)
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Findingreplicated ×3“Combining 9 effect sizes from 9 RCTs, we found a significant lowering effect of zinc supplementation on serum levels of TG (weighted mean difference (WMD): -17.08, 95% CI: -30.59, -3.58 mg/dL, P = 0.01) and TC (WMD: -26.16, 95% CI: -49.69, -2.62 mg/dL, P = 0.02).”
Quoted verbatim from Effects of zinc supplementation on lipid profile in patients with type 2 diabetes mellitus: A systematic review and meta-analysis of randomized controlled trials.. - Study
- meta-analysis
- Population
- Patients with type 2 diabetes mellitus; 9 randomized controlled trials, 424 patients overall
Effect -26.16 mean difference, 95% CI -49.69 to -2.62
Effects of zinc supplementation on lipid profile in patients with type 2 diabetes mellitus: A systematic review and meta-analysis of randomized controlled trials.2020PMID:32451277Permalink