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PapersPMID:31740020

Meta-analysis Comparing Combined Use of Eicosapentaenoic Acid and Statin to Statin Alone.

The American journal of cardiology2020The record ↗

01 · findings
2
02 · compound
1
03 · endpoints
2
04 · null
2
  1. Finding, very limited evidenceno effectIncidence of stroke
  2. Finding, very limited evidenceno effectAll-cause mortality
Population, every finding
Meta-analysis with trial sequential analysis of 5 RCTs (n=27,415) of EPA + statin vs statin alone; statin given as background therapy in both arms.

Every finding here is a null result.

What did not

2 findingsHow to read these marks →
  • all-cis-5,8,11,14,17-icosapentaenoic acid — no detected effect on incidence of stroke

    very limitedFindingNull result

    “However, combined therapy of EPA + statin demonstrated no significant association on incidence of stroke when compared with statin alone or all-cause mortality.”
    Quoted verbatim from Meta-analysis Comparing Combined Use of Eicosapentaenoic Acid and Statin to Statin Alone.
    Study
    meta-analysis

    Permalink

  • all-cis-5,8,11,14,17-icosapentaenoic acid — no detected effect on all-cause mortality

    very limitedFindingNull result

    “However, combined therapy of EPA + statin demonstrated no significant association on incidence of stroke when compared with statin alone or all-cause mortality.”
    Quoted verbatim from Meta-analysis Comparing Combined Use of Eicosapentaenoic Acid and Statin to Statin Alone.
    Study
    meta-analysis

    Permalink

Study record

Design
meta-analysis
Species
human
Population
Patients in 5 RCTs comparing EPA + statin versus statin alone, cardiovascular outcomes
Participants
27,415
Comparator
an active treatment
Duration
not recorded
Endpoints measured
5
Record
declined
Declined
another reason, stated per paper
Readings recorded
1