PapersPMID:31385062
Does L-carnitine supplementation affect serum levels of enzymes mainly produced by liver? A systematic review and meta-analysis of randomized controlled clinical trials.
- findings
- 2
- compound
- 1
- endpoints
- 2
(R)-carnitine- Study, every finding
- meta-analysis
- Dose studied, every finding
- 500 to 4000 mg/day
- Population, every finding
- Participants in 18 randomized trials (1161 participants) of L-carnitine supplementation; subgroups by dose, duration and liver disease not recorded here
What moved
How to read these marks →“L-carnitine supplementation significantly reduced serum ALT (MD = - 8.65 IU/L, 95% CI - 13.40, - 3.90), AST (MD = - 8.52 IU/L, 95% CI - 12.16, - 4.89), and GGTP (MD = - 8.80 IU/L, 95% CI - 13.67, - 3.92) levels.”
- Decreases aspartate aminotransferase
very limitedreplicated ×2
- Effect
- −8.52 mean difference, 95% CI −12.16 to −4.89
- Decreases alanine aminotransferase
very limitedreplicated ×3
- Effect
- −8.65 mean difference, 95% CI −13.4 to −3.9
Study record
- Design
- meta-analysis
- Species
- human
- Population
- participants in 18 randomized controlled trials of L-carnitine supplementation
- Participants
- 1,161
- Comparator
- not stated in the paper
- Duration
- not reported
- Endpoints measured
- 6