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Catalyst

(R)-carnitineFinding

(R)-carnitine decreases aspartate aminotransferase

lowersVery limited evidenceFindingreplicated ×2

01 · The sentence it was drawn from

“L-carnitine supplementation significantly reduced serum ALT (MD = - 8.65 IU/L, 95% CI - 13.40, - 3.90), AST (MD = - 8.52 IU/L, 95% CI - 12.16, - 4.89), and GGTP (MD = - 8.80 IU/L, 95% CI - 13.67, - 3.92) levels.”
Quoted verbatim from Does L-carnitine supplementation affect serum levels of enzymes mainly produced by liver? A systematic review and meta-analysis of randomized controlled clinical trials.
This finding among the 50 findings on its endpoint

(R)-carnitine

Aspartate aminotransferase

lowers

Effect as reported

−8.52mean difference

CI −12.16 to −4.89

Who
Participants in 18 randomized trials (1161 participants) of L-carnitine supplementation; subgroups by dose, duration and liver disease not recorded here
Dose studied
500 to 4000 mg/day

Very limited evidencePMID 31385062 · 2020

02 · The study

Study
meta-analysis
Duration
not reported

Evidence, by strength

  • strong
  • moderate
  • limited
  • very limitedthis finding
  • insufficient

03 · The paper

European journal of nutrition
What else it reported2 findings · 1 compound · 2 endpoints

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M701TW2P2958WFKAEGPY647Q