Papers/PMID:31372656
Long-lasting blood pressure lowering effects of nitrite are NO-independent and mediated by hydrogen peroxide, persulfides, and oxidation of protein kinase G1α redox signalling.
Cardiovascular research2020The record
1 finding · 1 compound · 1 endpoint
What it reported
How to read these marksWhat moved
1 finding
sodium nitrite — inhibits CAT
SpeculativeGrade F, Speculative. Mechanistic inference, no evidence found, or evidence weakened below D.Finding“This action was confirmed in complementary studies in which nitrite was found to be capable of inhibiting catalase activity in hepatic tissue in vitro (Supplementary material online, Figure S1).”
Quoted verbatim from Long-lasting blood pressure lowering effects of nitrite are NO-independent and mediated by hydrogen peroxide, persulfides, and oxidation of protein kinase G1α redox signalling.. - Study
- in vitro · not in humans
- Population
- hepatic tissue, in vitro
Long-lasting blood pressure lowering effects of nitrite are NO-independent and mediated by hydrogen peroxide, persulfides, and oxidation of protein kinase G1α redox signalling.2020PMID:31372656Permalink