PapersPMID:30642738
Effect of oral citrulline supplementation on whole body protein metabolism in adult patients with short bowel syndrome: A pilot, randomized, double-blind, cross-over study.
- findings
- 2
- compound
- 1
- endpoints
- 2
L-citrulline- Study, every finding
- crossover · 7 days
- Dose studied, every finding
- 0.18 g/kg/day oral citrulline for 7 days; iso-nitrogenous placebo, 13-day washout
- Population, every finding
- Nine adults with non-malignant short bowel syndrome, near-normal nutritional status, without artificial nutrition; postabsorptive state
What moved
How to read these marks →“Plasma citrulline concentration rose 17-fold (25 ± 9 vs. 384 ± 95 μmol/L) and plasma arginine 3-fold after oral citrulline supplementation (both p < 4 × 10-6).”
- Increases plasma citrulline concentration
very limitedreplicated ×2
- Increases plasma arginine concentration
very limitedreplicated ×2
Study record
- Design
- crossover trial
- Species
- human
- Population
- Adults with non-malignant short bowel syndrome in near-normal nutritional status, without artificial nutrition; oral citrulline dosed (form not stated)
- Participants
- 9
- Comparator
- placebo
- Duration
- 7 days
- Endpoints measured
- 9