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PapersPMID:30580081

L-theanine in the adjunctive treatment of generalized anxiety disorder: A double-blind, randomised, placebo-controlled trial.

Journal of psychiatric research2019The record ↗

  1. Finding, very limited evidenceno difference foundInsomnia Severity Index (ISI) total score

No finding here moved its endpoint.

What did not

1 findingHow to read these marks →
  • No detected effect on Insomnia Severity Index (ISI) total score

    very limited

    “Results revealed that adjunctive L-theanine did not outperform placebo for anxiety reduction on the HAMA (p = 0.73) nor insomnia severity on the Insomnia Severity Index (ISI; p = 0.35).”
    Study
    RCT
    Duration
    8 weeks
    Dose studied
    adjunctive L-theanine 450-900 mg
    Population
    Adults with DSM-5 generalized anxiety disorder, all on stable antidepressant treatment in both arms

Study record

Design
randomised controlled trial
Species
human
Population
46 participants with a DSM-5 diagnosis of generalized anxiety disorder on stable antidepressant treatment
Participants
46
Comparator
placebo
Duration
70 days
Endpoints measured
6