Papers/PMID:30108163
Randomised placebo-controlled trial of dietary glutamine supplements for postinfectious irritable bowel syndrome.
Gut2019The record
1 finding · 1 compound · 1 endpoint
What it reported
How to read these marksWhat moved
1 finding
L-glutamine — decreases stool frequency
LikelyGrade B, Likely. Human evidence with one recorded weakness, or capped at B by its design or by unread numbers.Finding“Glutamine also (i) reduced daily bowel movement frequency (p<0.0001), (ii) improved stool form on the Bristol Stool Scale (p<0.0001), and (iii) normalized intestinal hyperpermeability (where hyperpermeability is defined as an elevated urinary lactulose/mannitol ratio > 0.07) (p<0.0001).”
Quoted verbatim from Randomised placebo-controlled trial of dietary glutamine supplements for postinfectious irritable bowel syndrome.. - Study
- RCT
- Participants
- 106
- Duration
- 8 weeks
- Dose
- glutamine powder 5 g orally three times daily for 8 weeks
- Population
- adults with post-infectious diarrhoea-predominant IBS (IBS-D) and intestinal hyperpermeability
Randomised placebo-controlled trial of dietary glutamine supplements for postinfectious irritable bowel syndrome.2019PMID:30108163Permalink